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BPSL2015 BPSL2015 nagZ nagZ BPSL0500 BPSL0500 BPSL0657 BPSL0657 BPSL1763 BPSL1763 BPSL0499 BPSL0499 anmK anmK ddpX ddpX glk glk BPSL3316 BPSL3316 BPSL2014 BPSL2014
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
BPSL2015Putative membrane attached glycosyl hydrolase; Similar to Alteromonas sp. beta-hexosaminidase A precursor Cht60 SWALL:HEXA_ALTSO (SWALL:P48823) (598 aa) fasta scores: E(): 2.1e-59, 35.98% id in 628 aa, and to Ralstonia solanacearum putative hydrolase glycosidase protein rsc0769 or rs05085 SWALL:Q8Y1C1 (EMBL:AL646060) (734 aa) fasta scores: E(): 3.1e-152, 61.84% id in 684 aa; Belongs to the glycosyl hydrolase 3 family. (682 aa)    
Predicted Functional Partners:
nagZ
Putative beta-hexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
  
  
 
0.926
BPSL0500
Putative chitobiase; Similar to Serratia marcescens chitobiase precursor Chb SWALL:CHB_SERMA (SWALL:Q54468) (885 aa) fasta scores: E(): 2e-118, 46.94% id in 801 aa, and to Burkholderia cepacia putative chitinase Bcc1 SWALL:Q9F1K5 (EMBL:AB053088) (826 aa) fasta scores: E(): 0, 85.8% id in 831 aa. CDS is truncated at the C-terminus in comparison to orthologues.
    
 0.919
BPSL0657
Similar to Ralstonia solanacearum hypothetical protein rsc0514 or rs04986 SWALL:Q8Y222 (EMBL:AL646059) (352 aa) fasta scores: E(): 3.9e-76, 59.3% id in 344 aa, and to Pseudomonas aeruginosa hypothetical protein SWALL:Q9X4N9 (EMBL:AF116284) (338 aa) fasta scores: E(): 1.5e-56, 47.23% id in 343 aa.
    
 0.913
BPSL1763
Putative exported chitinase; Similar to Aeromonas sp chitinase II precursor SWALL:Q59145 (EMBL:D31818) (542 aa) fasta scores: E(): 1.7e-30, 34.61% id in 468 aa, and to the C-terminal region of Escherichia coli probable bifunctional chitinase/lysozyme precursor ChiA or b3338 SWALL:CHIA_ECOLI (SWALL:P13656) (897 aa) fasta scores: E(): 9.3e-30, 40.25% id in 318 aa. Note: In the C-terminal region of the E. coli entry is where the chitinase activity resides.
     
 0.908
BPSL0499
Phosphotransferase system, IIbc component; N-terminus is similar to the N-terminal region of Escherichia coli PTS system, N-acetylglucosamine-specific IIabc component NagE or PstN SWALL:PTAA_ECOLI (SWALL:P09323) (648 aa) fasta scores: E(): 1.2e-88, 52.51% id in 516 aa. Full length CDS is similar to Pseudomonas aeruginosa probable phosphotransferase system protein pa3761 SWALL:Q9HXN4 (EMBL:AE004794) (570 aa) fasta scores: E(): 1.2e-85, 56.15% id in 577 aa.
  
  
 0.488
anmK
Conserved hypothetical protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.
 
   
 0.477
ddpX
Putative D-alanyl-D-alanine dipeptidase; Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.
 
      0.440
glk
Glucokinase; Similar to Escherichia coli, and Escherichia coli O157:H7 glucokinase Glk or b2388 or z3654 or ecs3268 SWALL:GLK_ECOLI (SWALL:P46880) (321 aa) fasta scores: E(): 9e-49, 46.2% id in 316 aa and to Neisseria meningitidis glucokinase Glk or nma1607 or nmb1390 SWALL:GLK_NEIMA (SWALL:Q9JQX3) (328 aa) fasta scores: E(): 4.6e-57, 49.54% id in 327 aa; In the N-terminal section; belongs to the bacterial glucokinase family.
 
  
 0.425
BPSL3316
Similar to Rhizobium loti hypothetical protein Mll7250 SWALL:Q986Q7 (EMBL:AP003011) (294 aa) fasta scores: E(): 9.8e-26, 40.13% id in 289 aa.
 
    0.415
BPSL2014
Putative exported protein; No significant database matches.
       0.410
Your Current Organism:
Burkholderia pseudomallei
NCBI taxonomy Id: 272560
Other names: B. pseudomallei K96243, Burkholderia pseudomallei K96243, Burkholderia pseudomallei str. K96243, Burkholderia pseudomallei strain K96243
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